BDBM50327107 (R)-methyl 2-(naphthalen-2-yl)-2-((R)-piperidin-2-yl)acetate::CHEMBL1183494

SMILES COC(=O)[C@@H]([C@H]1CCCCN1)c1ccc2ccccc2c1

InChI Key InChIKey=DNRNSIJBSCBESJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327107   

TargetSodium-dependent dopamine transporter(Rat)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50327107((R)-methyl 2-(naphthalen-2-yl)-2-((R)-piperidin-2-...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]WIN 35428 from Sprague-Dawley rat striatal tissue after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50327107((R)-methyl 2-(naphthalen-2-yl)-2-((R)-piperidin-2-...)
Affinity DataIC50: 33.9nMAssay Description:Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50327107((R)-methyl 2-(naphthalen-2-yl)-2-((R)-piperidin-2-...)
Affinity DataIC50: 34nMAssay Description:Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50327107((R)-methyl 2-(naphthalen-2-yl)-2-((R)-piperidin-2-...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against dopamine receptor in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed