BDBM50327143 (R)-methyl 2-(4-aminophenyl)-2-((R)-piperidin-2-yl)acetate::CHEMBL1253709

SMILES COC(=O)[C@@H]([C@H]1CCCCN1)c1ccc(N)cc1

InChI Key InChIKey=RWBBMMXWHVZGGM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327143   

LigandPNGBDBM50327143((R)-methyl 2-(4-aminophenyl)-2-((R)-piperidin-2-yl...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT expressed in mouse N2A cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50327143((R)-methyl 2-(4-aminophenyl)-2-((R)-piperidin-2-yl...)
Affinity DataIC50: 34.5nMAssay Description:Displacement of [3H]WIN 35428 from Sprague-Dawley rat striatal tissue after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed