BDBM50327376 (1S,2R,5aR,7R,8aS,8bS)-7-(benzylamino)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one::CHEMBL1256587

SMILES C[C@@H](O[C@H]1CN2[C@@H]([C@H]3C[C@H](C[C@H]3C2=O)NCc2ccccc2)[C@@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=QTKOZNOELLHMIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327376   

TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50327376((1S,2R,5aR,7R,8aS,8bS)-7-(benzylamino)-2-((R)-1-(3...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50327376((1S,2R,5aR,7R,8aS,8bS)-7-(benzylamino)-2-((R)-1-(3...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in presence of 50% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed