BDBM50327407 5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-yl)-N-cyclopropylthiazol-2-amine::CHEMBL1258515

SMILES Clc1ccccc1-c1cc(nc(n1)-c1ccccn1)-c1cnc(NC2CC2)s1

InChI Key InChIKey=PKQKDZRSTCZBIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327407   

TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50327407(5-(6-(2-chlorophenyl)-2-(pyridin-2-yl)pyrimidin-4-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of bacterially expressed activated p38alpha pre-incubated 10 mins measured after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed