BDBM50327500 2-(5-(1H-indazol-5-yl)pyridin-3-yl)-1-fluoroethane-1,1-diyldiphosphonic acid::CHEMBL1258421

SMILES OP(O)(=O)C(F)(Cc1cncc(c1)-c1ccc2[nH]ncc2c1)P(O)(O)=O

InChI Key InChIKey=MLYBZHHGRJJXOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327500   

TargetFarnesyl pyrophosphate synthase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50327500(2-(5-(1H-indazol-5-yl)pyridin-3-yl)-1-fluoroethane...)
Affinity DataIC50: 700nMAssay Description:Inhibition of N-terminal His-tagged human FPPS expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50327500(2-(5-(1H-indazol-5-yl)pyridin-3-yl)-1-fluoroethane...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant N-terminal-His6 tagged FPPS expressed in Escherichia coli BL21 using [14C]IPP and GPP as substrate incubated for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed