BDBM50327683 2-(2-(Pyridin-2-yl)-6,7-dihydrooxazolo[4,5-c]pyridin-5(4H)-yl)-nicotinonitrile::CHEMBL1258544

SMILES N#Cc1cccnc1N1CCc2oc(nc2C1)-c1ccccn1

InChI Key InChIKey=RPQBRHRQPZEGIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327683   

TargetMetabotropic glutamate receptor 5(Human)
Sepracor

Curated by ChEMBL
LigandPNGBDBM50327683(2-(2-(Pyridin-2-yl)-6,7-dihydrooxazolo[4,5-c]pyrid...)
Affinity DataIC50: 110nMAssay Description:Modulation of human recombinant mGluR5 expressed in CHO cells assessed as inhibition of glutamate-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed