BDBM50327791 (R)-2-amino-2-(2,3-dihydro-1H-inden-2-yl)-1-(4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl)ethanone::CHEMBL1257283

SMILES Cc1c[nH]c2ncnc(N3CCN(CC3)C(=O)[C@H](N)C3Cc4ccccc4C3)c12

InChI Key InChIKey=ZKLRNDJLDZGUSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327791   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327791((R)-2-amino-2-(2,3-dihydro-1H-inden-2-yl)-1-(4-(5-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of AKT1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProline-rich AKT1 substrate 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327791((R)-2-amino-2-(2,3-dihydro-1H-inden-2-yl)-1-(4-(5-...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of PRAS40 phosphorylation at Thr246 in human LNCaP cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed