BDBM50327797 (R)-2-amino-3-(4-chlorophenyl)-1-(4-(quinazolin-4-yl)piperazin-1-yl)propan-1-one::CHEMBL1258330

SMILES N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ncnc2ccccc12

InChI Key InChIKey=KGZXBIKBYHLVNP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327797   

TargetRAC-beta serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327797((R)-2-amino-3-(4-chlorophenyl)-1-(4-(quinazolin-4-...)
Affinity DataIC50: 118nMAssay Description:Inhibition of AKT2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327797((R)-2-amino-3-(4-chlorophenyl)-1-(4-(quinazolin-4-...)
Affinity DataIC50: 179nMAssay Description:Inhibition of AKT3 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetProline-rich AKT1 substrate 1(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327797((R)-2-amino-3-(4-chlorophenyl)-1-(4-(quinazolin-4-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PRAS40 phosphorylation at Thr246 in human LNCaP cells after 1.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50327797((R)-2-amino-3-(4-chlorophenyl)-1-(4-(quinazolin-4-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of AKT1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed