BDBM50328078 CHEMBL1257304::N-(3-methoxyphenyl)-1-methyl-6-(3-methylbenzo[d]isoxazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES COc1cccc(Nc2nc(nc3n(C)ncc23)-c2cccc3onc(C)c23)c1

InChI Key InChIKey=JTLPAXYKBBZGEI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328078   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50328078(N-(3-methoxyphenyl)-1-methyl-6-(3-methylbenzo[d]is...)Copy SMILESCopy InChI

Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL