BDBM50328092 5-(3-Furyl)-2,2-dimethyl-N-(2-morpholin-4-ylethyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine::CHEMBL1257189

SMILES CC1(C)CCc2c(C1)c1c(nc2-c2ccoc2)sc2c(NCCN3CCOCC3)ncnc12

InChI Key InChIKey=DIQPQAKBMJIODR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328092   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328092(5-(3-Furyl)-2,2-dimethyl-N-(2-morpholin-4-ylethyl)...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328092(5-(3-Furyl)-2,2-dimethyl-N-(2-morpholin-4-ylethyl)...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328092(5-(3-Furyl)-2,2-dimethyl-N-(2-morpholin-4-ylethyl)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed