BDBM50328097 2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-3-ylmethyl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine::CHEMBL1257422

SMILES CC1(C)Cc2c(CO1)c(nc1sc3c(NCc4cccnc4)ncnc3c21)N1CCOCC1

InChI Key InChIKey=JKGFOIGGPUTHIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328097   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328097(2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-3-ylmethy...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328097(2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-3-ylmethy...)
Affinity DataIC50: 48nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328097(2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-3-ylmethy...)
Affinity DataIC50: 52nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed