BDBM50328100 2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-4-ylmethyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine::CHEMBL1257654

SMILES CC1(C)CCc2c(C1)c1c(nc2N2CCOCC2)sc2c(NCc3ccncc3)ncnc12

InChI Key InChIKey=ADXIPZNPTFVGDB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328100   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328100(2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-4-ylmethy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328100(2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-4-ylmethy...)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328100(2,2-Dimethyl-5-morpholin-4-yl-N-(pyridin-4-ylmethy...)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed