BDBM50328107 CHEMBL1257655::N-(2-Methoxybenzyl)-2,2-dimethyl-5-morpholin-4-yl-1,4-dihydro-2H-pyrano[4'',3'':4',5']thieno[3,2-d]pyrimidin-8-amine

SMILES COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3COC(C)(C)Cc3c21

InChI Key InChIKey=GXKKFFMAUKOFSO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328107   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328107(N-(2-Methoxybenzyl)-2,2-dimethyl-5-morpholin-4-yl-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PDE4B1 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328107(N-(2-Methoxybenzyl)-2,2-dimethyl-5-morpholin-4-yl-...)
Affinity DataIC50: 67nMAssay Description:Inhibition of PDE4A4 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50328107(N-(2-Methoxybenzyl)-2,2-dimethyl-5-morpholin-4-yl-...)
Affinity DataIC50: 119nMAssay Description:Inhibition of PDE4D3 expressed in yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed