BDBM50328171 5-methyl-N4-(2-morpholinoethyl)-N6-(4-(trifluoromethoxy)phenyl)pyrimidine-4,6-diamine::CHEMBL1258583

SMILES Cc1c(NCCN2CCOCC2)ncnc1Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=FXTQTTLOLCCIDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328171   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50328171(5-methyl-N4-(2-morpholinoethyl)-N6-(4-(trifluorome...)
Affinity DataEC50:  970nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed