BDBM50328391 CHEMBL1257443::diethyl 2-morpholino-4-phenyl-7-propylpyrrolo[1,2-f][1,2,4]triazine-5,6-dicarboxylate

SMILES CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(nc(nn12)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=RVQTWWBCQFZCAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328391   

TargetDiacylglycerol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328391(diethyl 2-morpholino-4-phenyl-7-propylpyrrolo[1,2-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50328391(diethyl 2-morpholino-4-phenyl-7-propylpyrrolo[1,2-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed