BDBM50328702 (S)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-yl)-2-(2-oxo-3-(phenylmethylsulfonamido)pyridin-1(2H)-yl)acetamide::CHEMBL257068

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-n1cccc(-[#7]S(=O)(=O)[#6]-c2ccccc2)c1=O)-[#6](=O)-c1nccs1

InChI Key InChIKey=VJOCYUHZYAJQFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328702   

TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328702((S)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328702((S)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50328702((S)-N-(5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed