BDBM50328772 2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen-2-yl)-1H-pyrazol-1-yl)phenyl)acetamide::CHEMBL1269839

SMILES NC(=O)Cc1cccc(c1)-n1nc(cc1NC(=O)Nc1cccc(Cl)c1Cl)-c1cccs1

InChI Key InChIKey=LUZMARQWKNWLOX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328772   

TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 48nMAssay Description:Binding affinity to unphosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 66nMAssay Description:Binding affinity to phosphorylated p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p38alpha autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328772(2-(3-(5-(3-(2,3-dichlorophenyl)ureido)-3-(thiophen...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed