BDBM50328785 CHEMBL1269841::N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(4-(3-(tetrahydrofuran-3-yl)phenyl)tetrahydro-2H-pyran-4-ylamino)butan-2-yl)acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCOCC1)c1cccc(c1)C1CCOC1

InChI Key InChIKey=KBLUIKVYUUMQFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328785   

TargetCathepsin D(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328785(N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(4-(...)
Affinity DataIC50: 150nMAssay Description:Inhibition of cathepsin-DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328785(N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(4-(...)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant BACE1 purified from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed