BDBM50329053 CHEMBL1270569::N4-(benzo[d][1,3]dioxol-4-yl)-N2-(3-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine

SMILES CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4OCOc34)n2)c1

InChI Key InChIKey=YZQWWQPQOLRGER-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329053   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329053(N4-(benzo[d][1,3]dioxol-4-yl)-N2-(3-(methylsulfony...)
Affinity DataIC50: 34nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329053(N4-(benzo[d][1,3]dioxol-4-yl)-N2-(3-(methylsulfony...)
Affinity DataIC50: 186nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed