BDBM50329054 CHEMBL1270670::N4-(6-chlorobenzofuran-7-yl)-N2-(3-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine

SMILES CS(=O)(=O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4ccoc34)n2)c1

InChI Key InChIKey=ZAARSQMNTKRNDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329054   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329054(N4-(6-chlorobenzofuran-7-yl)-N2-(3-(methylsulfonyl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329054(N4-(6-chlorobenzofuran-7-yl)-N2-(3-(methylsulfonyl...)
Affinity DataIC50: 897nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed