BDBM50329057 CHEMBL1270773::N4-(benzo[d]oxazol-7-yl)-N2-(3-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine

SMILES CS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4ncoc34)n2)c1

InChI Key InChIKey=KZCPXMFKBLMRRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329057   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329057(N4-(benzo[d]oxazol-7-yl)-N2-(3-(methylsulfonyl)phe...)
Affinity DataIC50: 219nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329057(N4-(benzo[d]oxazol-7-yl)-N2-(3-(methylsulfonyl)phe...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed