BDBM50329063 CHEMBL1271082::N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-(2-methoxyethyl)-N2-(3-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine

SMILES COCCN(c1ccnc(Nc2cccc(c2)S(C)(=O)=O)n1)c1c2OCOc2ccc1Cl

InChI Key InChIKey=SBGCOTWVZIWEKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329063   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329063(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-(2-methox...)
Affinity DataIC50: 246nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329063(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N4-(2-methox...)
Affinity DataIC50: 378nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed