BDBM50329065 CHEMBL1271187::N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)pyrimidine-2,4-diamine

SMILES C1CN(CCO1)c1cc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc(c1)N1CCOCC1

InChI Key InChIKey=VDTQYGNZODTYOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329065   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329065(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)py...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329065(N2-(3,5-dimorpholinophenyl)-N4-(1H-indazol-4-yl)py...)
Affinity DataIC50: 302nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed