BDBM50329068 CHEMBL1271393::N4-(1H-benzo[d][1,2,3]triazol-4-yl)-N2-(3,5-dimorpholinophenyl)pyrimidine-2,4-diamine

SMILES C1CN(CCO1)c1cc(Nc2nccc(Nc3cccc4nn[nH]c34)n2)cc(c1)N1CCOCC1

InChI Key InChIKey=JGQSHVPEBCAWDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329068   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329068(N4-(1H-benzo[d][1,2,3]triazol-4-yl)-N2-(3,5-dimorp...)
Affinity DataIC50: 115nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329068(N4-(1H-benzo[d][1,2,3]triazol-4-yl)-N2-(3,5-dimorp...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed