BDBM50329184 CHEMBL1269262::N-benzyl-N-isopropyl-2-(5-oxo-4-phenoxy-1-phenyl-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepin-6(5H)-yl)acetamide

SMILES CC(C)N(Cc1ccccc1)C(=O)CN1c2ccccc2-n2c(nnc2-c2ccccc2)C(Oc2ccccc2)C1=O

InChI Key InChIKey=OAWHDKLJQXYJNG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329184   

TargetCholecystokinin receptor type A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329184(N-benzyl-N-isopropyl-2-(5-oxo-4-phenoxy-1-phenyl-4...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]CCK8 from human CCK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50329184(N-benzyl-N-isopropyl-2-(5-oxo-4-phenoxy-1-phenyl-4...)
Affinity DataEC50:  628nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO cells assessed as induction of calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed