BDBM50329214 CHEMBL1271415::N-(3,5-dimethylphenyl)-5-(4-fluorophenyl)nicotinamide

SMILES Cc1cc(C)cc(NC(=O)c2cncc(c2)-c2ccc(F)cc2)c1

InChI Key InChIKey=XJXXETPSJSPVGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329214   

TargetSodium channel protein type 10 subunit alpha(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329214(N-(3,5-dimethylphenyl)-5-(4-fluorophenyl)nicotinam...)
Affinity DataIC50: 210nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329214(N-(3,5-dimethylphenyl)-5-(4-fluorophenyl)nicotinam...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329214(N-(3,5-dimethylphenyl)-5-(4-fluorophenyl)nicotinam...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of mouse NaV1.8 by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed