BDBM50329254 3-chloro-4-((3aR,6aS)-5-(3-(1-(methylsulfonyl)piperidin-4-yl)-3-phenylpropyl)octahydropyrrolo[3,4-c]pyrrole-2-carbonylsulfonyl)benzonitrile::CHEMBL1269387

SMILES CS(=O)(=O)N1CCC(CC1)C(CCN1C[C@H]2CN(C[C@H]2C1)C(=O)S(=O)(=O)c1ccc(cc1Cl)C#N)c1ccccc1

InChI Key InChIKey=KNHCVYDKPHQRAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329254   

TargetC-C motif chemokine 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329254(3-chloro-4-((3aR,6aS)-5-(3-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 215nMAssay Description:Inhibition of RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329254(3-chloro-4-((3aR,6aS)-5-(3-(1-(methylsulfonyl)pipe...)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed