BDBM50329882 4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)pyridin-2-amine::CHEMBL1271533

SMILES Nc1cc(ccn1)-c1cnn2cc(cnc12)-c1ccc(OCCN2CCOCC2)cc1

InChI Key InChIKey=HEPDAJRNJBNJAE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50329882   

LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 21nMAssay Description:Inhibition of c-SRC by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 40nMAssay Description:Inhibition of FLT1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 58nMAssay Description:Inhibition of KDR by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 164nMAssay Description:Inhibition of MNK1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 440nMAssay Description:Inhibition of LCK by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 840nMAssay Description:Inhibition of EphA2 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329882(4-(6-(4-(2-morpholinoethoxy)phenyl)pyrazolo[1,5-a]...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of RSK1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed