BDBM50329886 4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzenesulfonamide::CHEMBL1271642

SMILES NS(=O)(=O)c1ccc(Nc2ncc(o2)-c2ccc(O)c(O)c2)cc1

InChI Key InChIKey=OOPUEIPMZHMRKF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50329886   

LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 74nMAssay Description:Inhibition of FLT1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDR by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 130nMAssay Description:Inhibition of FLT3 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 970nMAssay Description:Inhibition of LCK by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of MNK1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of c-SRC by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of RSK1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50329886(4-(5-(3,4-dihydroxyphenyl)oxazol-2-ylamino)benzene...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphA2 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed