BDBM50330167 2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl)pyridin-2-yl)acetamide::CHEMBL1271554

SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1

InChI Key InChIKey=IUCRTXMTGDSAKX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330167   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University of TüBingen

Curated by ChEMBL
LigandPNGBDBM50330167(2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...)
Affinity DataIC50: 9nMAssay Description:Inhibition of p38alpha by immunosorbent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University of TüBingen

Curated by ChEMBL
LigandPNGBDBM50330167(2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...)
Affinity DataIC50: 9nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University of TüBingen

Curated by ChEMBL
LigandPNGBDBM50330167(2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed