BDBM50330333 CHEMBL1276023::Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-3-(5-sulfamoyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1H-pyrazole-4-carboxylate

SMILES CCOC(=O)c1c(nn(c1-c1ccccc1)-c1cccc(NN=C(C(C)=O)C(=O)OC(C)(C)C)c1)C(=O)Nc1nnc(s1)S(N)(=O)=O

InChI Key InChIKey=FXEZJYUGERELLE-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50330333   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330333(Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylide...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330333(Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylide...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330333(Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylide...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330333(Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylide...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330333(Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylide...)
Affinity DataKi:  30nMAssay Description:Inhibition of human carbonic anhydrase 2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

Curated by ChEMBL
LigandPNGBDBM50330333(Ethyl1-(3-(2-(1-tert-butoxy-1,3-dioxobutan-2-ylide...)
Affinity DataKi:  110nMAssay Description:Inhibition of human carbonic anhydrase 1 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed