BDBM50330572 CHEMBL1276846::N-[(R)-3-(4-Benzhydryl-piperazin-1-yl)-2-hydroxypropyl]-3,4-dichloro-N-cyclopropylmethylbenzenesulfonamide

SMILES O[C@@H](CN(CC1CC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1)CN1CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=FQUWLGICPYBBAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330572   

TargetBeta-secretase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50330572(N-[(R)-3-(4-Benzhydryl-piperazin-1-yl)-2-hydroxypr...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of BACE1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed