BDBM50331036 (S)-2-((S)-1-((S)-2-((4R,7S,10R)-10-amino-7-(4-hydroxybenzyl)-6,9-dioxo-1,2-dithia-5,8-diazacycloundecane-4-carboxamido)-3-(1H-imidazol-5-yl)propanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid::CHEMBL1275683

SMILES N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=NLSMVHZVUXJRBT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331036   

TargetLeucyl-cystinyl aminopeptidase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331036((S)-2-((S)-1-((S)-2-((4R,7S,10R)-10-amino-7-(4-hyd...)
Affinity DataKi:  5.51E+3nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331036((S)-2-((S)-1-((S)-2-((4R,7S,10R)-10-amino-7-(4-hyd...)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331036((S)-2-((S)-1-((S)-2-((4R,7S,10R)-10-amino-7-(4-hyd...)
Affinity DataKi:  1.69E+4nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331036((S)-2-((S)-1-((S)-2-((4R,7S,10R)-10-amino-7-(4-hyd...)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of catalytic activity of human recombinant aminopeptidase N expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed