BDBM50331106 (S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamino)-1,8-dioxooctan-2-ylcarbamate::CHEMBL1289931

SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCC(=O)NO)C(=O)NC1CCCC1

InChI Key InChIKey=YKINZQJOQFMNPU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331106   

TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-Lys(TFAc)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50331106((S)-tert-butyl 1-(cyclopentylamino)-8-(hydroxyamin...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human HDAC6 using Ac-RHKK(Ac)-ACC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed