BDBM50331149 CHEMBL1290254::N-(3-(trifluoromethyl)phenyl)-7-(3-(trifluoromethyl)pyridin-2-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine

SMILES FC(F)(F)c1cccc(Nc2ncnc3CN(CCc23)c2ncccc2C(F)(F)F)c1

InChI Key InChIKey=JWQSRYCSYMQUQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331149   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50331149(N-(3-(trifluoromethyl)phenyl)-7-(3-(trifluoromethy...)
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity at human recombinant TRPV1 assessed as inhibition of capsaicin-induced in intracellular calcium levels by cell-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed