BDBM50331358 CHEMBL1289178::rac-1-(3-chloro-4-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)benzyl)cyclopropanecarbonitrile

SMILES CC(O)(c1ccc(cc1)S(=O)(=O)c1ccc(CC2(CC2)C#N)cc1Cl)C(F)(F)F

InChI Key InChIKey=GXMKJDRDNOREPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331358   

LigandPNGBDBM50331358(rac-1-(3-chloro-4-(4-(1,1,1-trifluoro-2-hydroxypro...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331358(rac-1-(3-chloro-4-(4-(1,1,1-trifluoro-2-hydroxypro...)
Affinity DataIC50: 184nMAssay Description:Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed