BDBM50331365 (S)-3'-(2-fluoroethyl)-4'-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)biphenyl-4-carbonitrile::CHEMBL1289629

SMILES C[C@](O)(c1ccc(cc1)S(=O)(=O)c1ccc(cc1CCF)-c1ccc(cc1)C#N)C(F)(F)F

InChI Key InChIKey=CCRNRHWCUIODMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331365   

LigandPNGBDBM50331365((S)-3'-(2-fluoroethyl)-4'-(4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50331365((S)-3'-(2-fluoroethyl)-4'-(4-(1,1,1-trifluoro-2-hy...)
Affinity DataIC50: 20.7nMAssay Description:Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed