BDBM50331371 CHEMBL1290275::N-((3R,4R)-4-(4'-cyanobiphenyl-4-yl)-1-ethylpyrrolidin-3-yl)propane-2-sulfonamide

SMILES CCN1C[C@H](NS(=O)(=O)C(C)C)[C@H](C1)c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key InChIKey=OXFGNMCLRIFXSJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331371   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331371(N-((3R,4R)-4-(4'-cyanobiphenyl-4-yl)-1-ethylpyrrol...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331371(N-((3R,4R)-4-(4'-cyanobiphenyl-4-yl)-1-ethylpyrrol...)
Affinity DataEC50:  7.90E+3nMAssay Description:Positive modulation of human GluA2 flip receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed