BDBM50331571 CHEMBL1289422::N-(4-amino-3,4-dioxobutan-2-yl)-2-chloro-4-ethoxy-3-(trifluoromethyl)benzamide

SMILES CCOc1ccc(C(=O)NC(C)C(=O)C(N)=O)c(Cl)c1C(F)(F)F

InChI Key InChIKey=QHDNYLUGIIWMMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331571   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331571(N-(4-amino-3,4-dioxobutan-2-yl)-2-chloro-4-ethoxy-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331571(N-(4-amino-3,4-dioxobutan-2-yl)-2-chloro-4-ethoxy-...)
Affinity DataIC50: 195nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed