BDBM50331572 CHEMBL1289423::N-(4-(1H-pyrazol-3-ylamino)-3,4-dioxobutan-2-yl)-2-chloro-4-ethoxy-3-(trifluoromethyl)benzamide

SMILES CCOc1ccc(C(=O)NC(C)C(=O)C(=O)Nc2ccn[nH]2)c(Cl)c1C(F)(F)F

InChI Key InChIKey=SVWMYRNQZSRCPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331572   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331572(N-(4-(1H-pyrazol-3-ylamino)-3,4-dioxobutan-2-yl)-2...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331572(N-(4-(1H-pyrazol-3-ylamino)-3,4-dioxobutan-2-yl)-2...)
Affinity DataIC50: 91.2nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed