BDBM50331575 2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-dioxoheptan-3-yl)-4-(pyridin-2-ylmethoxy)-3-(trifluoromethyl)benzamide::CHEMBL1289750

SMILES CCCCC(NC(=O)c1ccc(OCc2ccccn2)c(c1Cl)C(F)(F)F)C(=O)C(=O)Nc1ccn(C)n1

InChI Key InChIKey=BLXZSNSXPVRKAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331575   

TargetCathepsin S(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331575(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCathepsin K(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331575(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)
Affinity DataIC50: 47.9nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed