BDBM50331799 CHEMBL1289329::N-methyl-3-phenyl-6-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)benzo[b]thiophene-2-carboxamide

SMILES CCC(O)(c1cn(Cc2ccc3c(c(sc3c2)C(=O)NC)-c2ccccc2)nn1)C(F)(F)F

InChI Key InChIKey=OGPQDWMXVJCSIW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331799   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331799(N-methyl-3-phenyl-6-((4-(1,1,1-trifluoro-2-hydroxy...)
Affinity DataIC50: 223nMAssay Description:Inhibition of human recombinant 5-lipoxygenase assessed as arachidonic acid oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331799(N-methyl-3-phenyl-6-((4-(1,1,1-trifluoro-2-hydroxy...)
Affinity DataIC50: 263nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331799(N-methyl-3-phenyl-6-((4-(1,1,1-trifluoro-2-hydroxy...)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of labeled MK-499 from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed