BDBM50331807 1,1,1-trifluoro-2-(1-((3-phenylbenzo[b]thiophen-6-yl)methyl)-1H-1,2,3-triazol-4-yl)butan-2-ol::CHEMBL1290766

SMILES CCC(O)(c1cn(Cc2ccc3c(csc3c2)-c2ccccc2)nn1)C(F)(F)F

InChI Key InChIKey=OAPVSBAGXAEPFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331807   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331807(1,1,1-trifluoro-2-(1-((3-phenylbenzo[b]thiophen-6-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant 5-lipoxygenase assessed as arachidonic acid oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331807(1,1,1-trifluoro-2-(1-((3-phenylbenzo[b]thiophen-6-...)
Affinity DataIC50: 598nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed