BDBM50331884 6-chloro-8-(phenylethynyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid::CHEMBL1290321

SMILES OC(=O)C1=Cc2cc(Cl)cc(C#Cc3ccccc3)c2OC1C(F)(F)F

InChI Key InChIKey=OPSPKIBCFWXEJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331884   

TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331884(6-chloro-8-(phenylethynyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331884(6-chloro-8-(phenylethynyl)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed