BDBM50331933 2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2-dihydroquinolin-6-yloxy)-N-(2-phenylpropan-2-yl)acetamide::CHEMBL1290102

SMILES Cc1cc(on1)-c1c(CCc2ccccc2)c2cc(OCC(=O)NC(C)(C)c3ccccc3)ccc2[nH]c1=O

InChI Key InChIKey=BOFQEGROHMEPMB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331933   

TargetAdenosine receptor A1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331933(2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331933(2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2...)
Affinity DataKi:  31nMAssay Description:Antagonist activity at human adenosine A2B receptor transfected in CHO cells assessed as inhibition of NECA-induced cAMP accumulation treated 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331933(2-(3-(3-methylisoxazol-5-yl)-2-oxo-4-phenethyl-1,2...)
Affinity DataKi:  2.83E+3nMAssay Description:Displacement of [3H]SCH58261 from human adenosine A2A receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed