BDBM50331994 2-(benzyloxy)-1-(4-(4-fluorophenyl)piperazin-1-yl)ethanone::CHEMBL1290668

SMILES Fc1ccc(cc1)N1CCN(CC1)C(=O)COCc1ccccc1

InChI Key InChIKey=PNMZFJOPBFIRGI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331994   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50331994(2-(benzyloxy)-1-(4-(4-fluorophenyl)piperazin-1-yl)...)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed