BDBM50332084 2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-yl)acetamide::CHEMBL1288098::US9796706, Compound 85

SMILES COc1ccc(CC(=O)Nc2ccsc2-c2cnccn2)cc1

InChI Key InChIKey=RVEHZFOKUTZKBA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50332084   

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Erk2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332084(2-(4-methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-...)
Affinity DataIC50: 5.05E+3nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
Go to US Patent