BDBM50332833 (8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-3,4,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one::CHEMBL1630911

SMILES C[C@]12CC[C@H]3[C@@H](CC=C4CCCC[C@]34CO)[C@@H]1CCC2=O

InChI Key InChIKey=VHEGBHRCHSDJHJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332833   

TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332833((8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-3...)
Affinity DataKi:  1.00E+3nMAssay Description:The binding affinity was determined on Cytochrome P450 19A1 by analysis of Dixon plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332833((8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-3...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human placental aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Tohoku College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50332833((8R,9S,10S,13S,14S)-10-(hydroxymethyl)-13-methyl-3...)
Affinity DataIC50: 6.90E+3nMAssay Description:In vitro competitive inhibitory activity was measured on Cytochrome P450 19A1 of human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed