BDBM50332947 (S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulfonamido)-N-hydroxyacetamide::CHEMBL1632637

SMILES COc1ccc(cc1)S(=O)(=O)N(C[C@H](O)CO)CC(=O)NO

InChI Key InChIKey=FAJZOFHZLDUFEM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50332947   

TargetCollagenase 3(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  8nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  24nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  160nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMatrilysin(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332947((S)-2-(N-(2,3-dihydroxypropyl)-4-methoxyphenylsulf...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed