BDBM50332953 (S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfonamido)-N-hydroxyacetamide::CHEMBL1632642

SMILES OC[C@@H](O)CN(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=OEHVKBKRRIUTOR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50332953   

TargetCollagenase 3(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  18nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  48nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  60nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  742nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMatrilysin(Human)
Protera

Curated by ChEMBL
LigandPNGBDBM50332953((S)-2-(N-(2,3-dihydroxypropyl)biphenyl-4-ylsulfona...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed